PhD, Leiden University, 2025
M.S. Biomedical Sciences, Leiden University, The Netherlands, 2019
B.S. Biochemistry, University Autònoma of Barcelona, Spain 2016
Research Interests
Forward programming, mammalian synthetic biology, stem cell engineering
Publications
- Blanch-Asensio, A., Ploessl, D., Wang, N., Mummery, C.L., Galloway, K.E. & Davis, R. P. STRAIGHT-IN Dual: a platform for dual, single-copy integrations of DNA payloads and gene circuits into human pluripotent stem cells. bioRxiv. 2024.
- Blanch-Asensio, A., Grandela, C., Mummery, C.L., & Davis, R. P. STRAIGHT-IN: a method for rapidly generating panels of genetically modified human pluripotent stem cell lines. Nature Protocols. 2024.
- Blanch-Asensio*, A., Grandela*, C., Brandao, K. O., Korte, T. de, Mei, H., Ariyurek, Y., Yiangou, L., Mol, M. P. H., Meer, B. J. van, Kloet., S. L., Mummery, C.L., & Davis, R. P. STRAIGHT-IN enables high-throughput targeting of large DNA payloads in human pluripotent stem cells. Cell Reports Methods. 2022.
- Blanch-Asensio, A., Vaart, B. Van Der, Vinagre, M., Groen, E., Arendzen, C., Freund, C., Geijsen, N., Mummery, C. L., & Davis, R. P. Generation of AAVS1 and CLYBL STRAIGHT-IN v2 acceptor human iPSC lines for integrating DNA payloads. Stem Cell Research. 2023.
- Yiangou, L., Blanch-Asensio, A., de Korte, T., Miller, D. C., van Meer, B. J., Mol, M. P. H., van den Brink, L., Brandão, K. O., Mummery, C. L., & Davis, R. P. Optogenetic Reporters Delivered as mRNA Facilitate Repeatable Action Potential and Calcium Handling Assessment in Human iPSC-Derived Cardiomyocytes. Stem Cells. 2022
- Popović, N. Z., Blanch-Asensio, A., Visser, T., Mummery, C. L., Davis, R. P., & Yiangou, L. Generation of two induced pluripotent stem cell (iPSC) lines carrying the Brugada Syndrome-associated mutation SCN5A-R282H. Stem Cell Research. 2024.
- van den Brink, L., Brandão, K. O., Yiangou, L., Blanch-Asensio, A., Mol, M. P. H., Mummery, C. L., Verkerk, A. O., & Davis, R. P. The Linkage Phase of the Polymorphism KCNH2-K897T Influences the Electrophysiological Phenotype in hiPSC Models of LQT2. Frontiers in Physiology. 2021.
- Novoa, J., Westra, I., Steeneveld, E., Fonseca Neves, N., Daleman, L., Blanch-Asensio, A., Davis, R.P., Carlotti, F., Freund, C., Rabelink, T., Meij, P., & Wieles, B. (2024). Validating human induced pluripotent stem cell-specific quality control tests for the release of an intermediate drug product in a Good Manufacturing Practice quality system. Cytotherapy. 2024.
- Johnstone, C., Love, K., Kabaria, S., Jones, R., Blanch-Asensio, A., Ploessl, D., Peterman, E., Lee, R., Yun, J., Oakes, C., Mummery, C., Davis, R., DeKosky, B., Zandstra, P., Galloway, K. Gene syntax defines supercoiling-mediated transcriptional feedback. bioRxiv. 2025.
Beyond the lab
Hiking, travelling, sports, reading, nature
Contact
LinkedIn
Google Scholar
ablanch (at) mit.edu
