PhD Graduate Student, Leiden University
M.S. Biomedical Sciences, Leiden University, The Netherlands, 2019
B.S. Biochemistry, University Autònoma of Barcelona, Spain 2016
Research Interests
Forward programming, mammalian synthetic biology, stem cell engineering
Publications
- Blanch-Asensio, A., Ploessl, D., Wang, N., Mummery, C.L., Galloway, K.E. & Davis, R. P. STRAIGHT-IN Dual: a platform for dual, single-copy integrations of DNA payloads and gene circuits into human pluripotent stem cells. bioRxiv. 2024.
- Blanch-Asensio, A., Grandela, C., Mummery, C.L., & Davis, R. P. STRAIGHT-IN: a method for rapidly generating panels of genetically modified human pluripotent stem cell lines. Nature Protocols. 2024.
- Blanch-Asensio*, A., Grandela*, C., Brandao, K. O., Korte, T. de, Mei, H., Ariyurek, Y., Yiangou, L., Mol, M. P. H., Meer, B. J. van, Kloet., S. L., Mummery, C.L., & Davis, R. P. STRAIGHT-IN enables high-throughput targeting of large DNA payloads in human pluripotent stem cells. Cell Reports Methods. 2022.
- Blanch-Asensio, A., Vaart, B. Van Der, Vinagre, M., Groen, E., Arendzen, C., Freund, C., Geijsen, N., Mummery, C. L., & Davis, R. P. Generation of AAVS1 and CLYBL STRAIGHT-IN v2 acceptor human iPSC lines for integrating DNA payloads. Stem Cell Research. 2023.
- Yiangou, L., Blanch-Asensio, A., de Korte, T., Miller, D. C., van Meer, B. J., Mol, M. P. H., van den Brink, L., Brandão, K. O., Mummery, C. L., & Davis, R. P. Optogenetic Reporters Delivered as mRNA Facilitate Repeatable Action Potential and Calcium Handling Assessment in Human iPSC-Derived Cardiomyocytes. Stem Cells. 2022
- Popović, N. Z., Blanch-Asensio, A., Visser, T., Mummery, C. L., Davis, R. P., & Yiangou, L. Generation of two induced pluripotent stem cell (iPSC) lines carrying the Brugada Syndrome-associated mutation SCN5A-R282H. Stem Cell Research. 2024.
- van den Brink, L., Brandão, K. O., Yiangou, L., Blanch-Asensio, A., Mol, M. P. H., Mummery, C. L., Verkerk, A. O., & Davis, R. P. The Linkage Phase of the Polymorphism KCNH2-K897T Influences the Electrophysiological Phenotype in hiPSC Models of LQT2. Frontiers in Physiology. 2021.
- Novoa, J., Westra, I., Steeneveld, E., Fonseca Neves, N., Daleman, L., Blanch-Asensio, A., Davis, R.P., Carlotti, F., Freund, C., Rabelink, T., Meij, P., & Wieles, B. (2024). Validating human induced pluripotent stem cell-specific quality control tests for the release of an intermediate drug product in a Good Manufacturing Practice quality system. Cytotherapy. 2024.
- Johnstone, C., Love, K., Kabaria, S., Jones, R., Blanch-Asensio, A., Ploessl, D., Peterman, E., Lee, R., Yun, J., Oakes, C., Mummery, C., Davis, R., DeKosky, B., Zandstra, P., Galloway, K. Gene syntax defines supercoiling-mediated transcriptional feedback. bioRxiv. 2025.
Beyond the lab
Hiking, travelling, sports, reading, nature
Contact
LinkedIn
Google Scholar
ablanch (at) mit.edu
